Found 18 matching trials
Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multiple Sclerosis PHASE2 Multiple sclerosis is the most common inflammatory disease of the central n...
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Johns Hopkins University
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A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis PHASE3 This is a Phase IIIb, single-arm, multicenter, OLE study. Participants rece...
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Active Not Recruiting
Location
Barrow Neurological Institute
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A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis PHASE1 The main purpose of this study is to evaluate the safety and tolerability o...
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Active Not Recruiting
Location
Profound Research, LLC
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Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis PHASE4 The proposed study is a pilot study of ublituximab involving people with mu...
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Johns Hopkins University
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National Project on Vaccines, COVID-19 and Frail Patients N/A This is a multicentre observational study with the aim of evaluating the an...
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IRCCS Istituto Tumori Giovanni Paolo II
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A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS) PHASE3 This is a randomized, double blind, controlled, parallel group, multicenter...
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Active Not Recruiting
Location
Alabama Neurology Associates
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Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis PHASE4 This study is a prospective, multi-center, randomized, double blinded, plac...
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Yale School of Medicine
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An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment PHASE3 The study will evaluate the physical impact of MS from participant's perspe...
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CHU Amiens Hopital Sud
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A Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to Methotrexate (FILM) PHASE3 This study will evaluate the efficacy and safety of ocrelizumab, compared w...
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Multiple Locations
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Assessing the Effects of Ongoing Ocrelizumab (OCR) Therapy on Fatigue and Cognition in Veterans With Multiple Sclerosis NA This study seeks to assess the effects of long-term ocrelizumab therapy on ...
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John D. Dingell VA Medical Center
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